Adenoviral Vectors for Gene Therapy
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ISBN-13:
9780128005101
Publisher:
Elsevier Science
Date of publication:
03/10/2016
sold:
E-Book PDF
Format:
Pages:
868
File size:
14 MB
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This product can take a few minutes to download.
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Adenoviral vectors for gene therapy, Second Edition provides a detailed, comprehensive coverage of gene delivery vehicles, which are based on adenovirus, which is formed as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of diseases, which makes gene therapy rapidly growing field of research.
This book presents topics ranging from the basic biology of the adenoviruses, through the construction and purification of adenoviral vectors, ultra vectorology, as well as the use of adenoviral vectors in preclinical animal models, the final consideration of regulatory issues related to the test therapy clinical human gene This wide scope of information It provides a solid overview of the field, which allows the reader to get a complete picture of the development and use of adenoviral vectors.
Provides complete coverage of the basic biology of the adenoviruses, and their construction, distribution and purification of adenoviral vectorsIntroduces common strategies for the development of adenoviral vectors, along with the best practices of their improvementDemonstrates noninvasive imaging of adenovirus-mediated usefulness of gene transferDiscusses adenoviral vectors modelsConsiders animals rules diseases Federal Drug Administration for clinical tests on humans
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